Plant Transcription Factor Database
Previous version: v3.0
Tarenaya hassleriana
NF-YA Family
Species TF ID Description
XP_010519069.1NF-YA family protein
XP_010519750.1NF-YA family protein
XP_010519751.1NF-YA family protein
XP_010519753.1NF-YA family protein
XP_010519754.1NF-YA family protein
XP_010519755.1NF-YA family protein
XP_010519756.1NF-YA family protein
XP_010520177.1NF-YA family protein
XP_010520178.1NF-YA family protein
XP_010536085.1NF-YA family protein
XP_010536086.1NF-YA family protein
XP_010540079.1NF-YA family protein
XP_010542390.1NF-YA family protein
XP_010542391.1NF-YA family protein
XP_010542392.1NF-YA family protein
XP_010542393.1NF-YA family protein
XP_010543859.1NF-YA family protein
XP_010543860.1NF-YA family protein
XP_010543861.1NF-YA family protein
XP_010543862.1NF-YA family protein
XP_010544186.1NF-YA family protein
XP_010544187.1NF-YA family protein
XP_010544188.1NF-YA family protein
XP_010544189.1NF-YA family protein
XP_010544190.1NF-YA family protein
XP_010544191.1NF-YA family protein
XP_010544192.1NF-YA family protein
XP_010552240.1NF-YA family protein
XP_010552241.1NF-YA family protein
XP_010552242.1NF-YA family protein
XP_010552243.1NF-YA family protein
XP_010555018.1NF-YA family protein
XP_010555019.1NF-YA family protein
XP_010557797.1NF-YA family protein
XP_010557970.1NF-YA family protein
XP_010557971.1NF-YA family protein
XP_010557972.1NF-YA family protein
XP_010557973.1NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982